As Florida's largest aquatic preserve and the sparse development along its shores, Big Bend Seagrasses Aquatic Preserve has a wealth of recreational opportunities, including swimming, wildlife viewing, boating, canoeing, kayaking, scalloping and fishing. There are several state parks, national wildlife refuges and two paddling trails.

• Big Bend Saltwater Paddling Trail
• Florida Circumnavigational Saltwater Paddling Trail
• Segment 5 - Crooked River to St. Marks
• Segment 6 - Big Bend
• Cedar Key Scrub State Reserve
• Econfina River State Park
• Fanning Springs State Park
• Lower Suwannee National Wildlife Refuge
• Manatee Springs State Park
• St. Marks National Wildlife Refuge
• Waccasassa Bay Preserve State Park